Groundbreaking research of collaborators and satisfied customers in a broad field of applications.

Latest publications in the field of:

Bioprinting / cell dispensing


A drop-on-demand bioprinting approach to spatially arrange multiple cell types and monitor their cell-cell interactions towards vascularization based on endothelial cells and mesenchymal stem cells.
Joshua Weygant, Fritz Koch, Katrin Adam, Kevin Troendle, Roland Zengerle, Günter Finkenzeller, Sabrina Kartmann, Peter Koltay, Stefan Zimmermann

bioRxiv, July 2022


Scalable fabrication of renal spheroids and nephron-like tubules by bioprinting and controlled self-assembly of epithelial cells.
Kevin Troendle, Ludovica Rizzo, Roman Pichler, Fritz Koch, Ahmad Itani, Roland Zengerle, Soeren S Lienkamp, Peter Koltay and Stefan Zimmermann

Biofabrication 2021, in press


In vivo evaluation of bioprinted prevascularized bone tissue
Patrick Rukavina, Fritz Koch, Maximilian Wehrle, Kevin Tröndle, G. Björn Stark, Peter Koltay, Stefan Zimmermann, Roland Zengerle, Florian Lampert, Sandra Strassburg, Günter FinkenzellerFilip Simunovic

BioTechnology and Bioengineering, 2020, (117), Issue 12, 3902 - 3911


Bioprinting of high cell‐density constructs leads to controlled lumen formation with self‐assembly of endothelial cells.
Kevin Tröndle, Fritz Koch, Günter Finkenzeller, G. Björn Stark, Roland Zengerle, Peter Koltay and Stefan Zimmermann

J Tissue Eng Regen Med. 2019, 13, 1883–1895


Mass spectrometry imaging


Pharmacological inhibition of MERTK induces in vivo retinal degeneration: a multimodal imaging ocular safety assessment
Gregory Hamm et al.

Archives of Toxicology 2022, 96, pages 613–624


Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood–brain barrier
Dominika Luptáková, Theodosia Vallianatou, Anna Nilsson, Reza Shariatgorji, Margareta Hammarlund-Udenaes, Irena Loryan and Per E. Andrén

Molecular Psychiatry 2021, 26:77327745


Evaluation of UVC Decontamination of Clinical Tissue Sections forSpatially Resolved Analysis by Mass Spectrometry Imaging (MSI).
Andreas Dannhorn, Stephanie Ling, Steven Powell, Eileen McCall, Gareth Maglennon, Gemma N. Jones,Andrew J. Pierce, Nicole Strittmatter, Gregory Hamm, Simon T. Barry, Josephine Bunch,Richard J. A. Goodwin, and Zoltan Takats

Anal.Chem. 2021, 93, 2767−2775


Sensors fabrication


A Versatile Capacitive Sensing Platform for the Assessment of the Composition in Gas Mixtures.
Jörgen Sweelssen, Huib Blokland, Timo Rajamäki, Risto Sarjonen and Arjen Boersma

Micromachines 2020, 11(2), 116


Searching for bed bugs: The design, development, and evaluation of an oscillator-based trans-2-hexenal sensor array.
Nikhil Bajaj, Natalie C. Giampietro, Katherine Mao, Mary E. Rushton, Neil A. Spomer and Jeffrey F. Rhoads

Sensors and Actuators B: Chemical, Volume 333, 15 April 2021, 129161


Detection of Traumatic Brain Injury Protein Biomarkers With Resonant Microsystems.
Michael J. Wadas, Mackenzie Tweardy, Nikhil Bajaj, Allison K. Murray, George T.-C. Chiu, Eric A. Nauman, Jeffrey F. Rhoads

IEEE Senors Letters, Volume 1, Issue 6, December 2017


Fabrication of Ag nanorods on micropost array for a metal-enhanced fluorescence substrate with a high signal-to-background ratio.
Xun Lu, Seongmin Lee, Jun Kim, Naseem Abbas, Mohsin Ali Badshah, Seok-min Kim

Biosensors and Bioelectronics, Volume 175, 1 March 2021, 112881


Lateral flow assays


Signal enhancement on gold nanoparticle-based lateral flow tests using cellulose nanofibers.
Daniel Quesada-González, Christina Stefani, Israel González, Alfredode la Escosura-Muñiz Neus Domingo, Pere Mutjé, Arben Merkoçia

Biosensors and Bioelectronics, Volume 141, 15 September 2019, 111407


Uranium (VI) detection in groundwater using a gold nanoparticle/paper-based lateral flow device.
Daniel Quesada-González, Grace A. Jairo, Robert C. Blake II, Diane A. Blake & Arben Merkoçi

Scientific Reports volume 8, Article number: 16157 (2018) Cite this article

Microneedle production / drug loading


Engineering of an automated nano-droplet dispensing system for fabrication of antigen-loaded dissolving microneedle arrays.

JihuiLee, Koenvan der Maaden, Gerrit Gooris, Conor O'Mahony, Wim Jiskoot, Joke Bouwstra International Journal of Pharmaceutics, Volume 600, 1 May 2021, 120473


Animal free toxicological testing


Defining corneal chemical burns: A novel exact and adjustable ocular model.
Markus Glaudo, Claudia Panfil and Norbert F. Schrage

Toxicology Reports 2021, 8, 1200–1206


Lithography / Additive methods


Nanoimprint meets microfluidics: Development of metal wires from nanoparticle inkfilled capillaries
Barbara Horváth, Barbora Křivová and Helmut Schift

Micro and Nano Engineering, 2019 (3), 22 – 30




A new and highly sensitive TLC method to measure hypericin using chemiluminescence.
Andreas Lotz, Peter Habermehl & Bernd Spangenberg

Journal of Liquid Chromatography & Related Technologies, 2017 (40), Issue 5-6, 287 -291



Food science


Revealing how maltodextrin-containing droplets dry using optical coherence tomography
Erik J.G. Sewalt, J. Kalkman, J.R. van Ommen, Gabrie M.H. Meesters, V.van Steijn

Food Research International, Volume 17, July 2022, 111049

Protective effect of carrier matrices on survival of Lactobacillus plantarum WCFS1 during single droplet drying explained by particle morphology development.
Siemons, E.M.J. Vaessen, S.E.Oosterbaan van Peski, R.M.Boom and M.A.I. Schutyser

Journal of Food Engineering, 2021, (292), 110263

Dextrose equivalence of maltodextrins determines particle morphology development during single sessile droplet drying
I. Siemons, R. G. A. Politiek, R. M. Boom, R. G. M. van der Sman, M. A. I. Schutyser

Food Research International, Volume 131, May 2020, 108988




Selectively-deposited energetic materials: A feasibility study of the piezoelectric inkjet printing of nanothermites.
Alison K. Murray, Whitney A. Novotny, Trevor J. Fleck, I. Emre Gunduz, Steven F. Son, George T.-C. Chiu, Jeffrey F. Rhoads

Additive Manufacturing, Volume 22, August 2018, Pages 69-74


A Novel Fabrication Technique for Electrodes of PEM Water Electrolyzers.
Melanie Bühler, Carolin Klose, Friedmann Hegge, Thomas Lickert, Simon Thiele

ECS Transactions, Volume 80, Number 8, 2017


Simple fabrication of 12 μm thin nanocomposite fuel cell membranes by direct electrospinning and printing.
Matthias Breitwieser, Carolin Klose, Matthias Klingele, Armin Hartmann, Johannes Erben, Hyeongrae Cho, Jochen Kerres, Roland Zengerle, Simon Thiele

Journal of Power Sources, Volume 337, 1 January 2017, Pages 137-144


Target preparation for nuclear physics experiments


Development and characterization of a Drop-on-Demand inkjet printing system for nuclear target fabrication.
R. Haas, S. Lohse, Ch. E. Düllmann, K. Eberhardt, C. Mokry, J. Runke

Nuclear Instruments and Methods in Physics, Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Volume 874, 1 December 2017, Pages 43-49


Basic research


Automated estimation of contact angle on hydrophobic fibers using a microrobotic platform.
Juha Hirvonen, Yuli Lai, Pasi Kallio, Gisela Cunha, Orlando Rojas

2016 IEEE International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M-NANO) 18-22 July, Chongqing


Atmospheric Photopolymerization of Acrylamide Enabled by Aqueous Glycerol Mixtures: Characterization and Application for Surface‐Based Microfluidics.
Tobias Gleichmann, Arpad Rostas, Jakob Wörner, Erik Schleicher, Ludwig Gutzweiler, Boris Hamouda, Roland Zengerle, Peter Koltay, Lutz Riegger

Macromolecular Materials and Engineering, 20 July 2017, Volume 302, Issue 10, 1600518


Dextrose equivalence of maltodextrins determines particle morphology development during single sessile droplet drying.
I. Siemons, R.G.A. Politiek, R.M. Boom, R.G.M. van der Sman, M.A.I. Schutyser

Food Research International, Volume 131, May 2020, 108988


Protective effect of carrier matrices on survival of Lactobacillus plantarum WCFS1 during single droplet drying explained by particle morphology development..
I. Siemons, E.M.J. Vaessen, S.E. Oosterbaan van Peski, R.M. Boom, M.A.I. Schutyser

Journal of Food Engineering, Volume 292, March 2021, 110263


Revealing how maltodextrin-containing droplets dry using optical coherence tomography.
Erik J.G. Sewalt, J. Kalkman, J.R. van Ommen, Gabrie M.H. Meesters, V. van Steijn

Food Research International, Volume 157, July 2022, 111049


High-resolution thermography and modelling allows for improved characterization of drying sessile single droplets.
N.M. Eijkelboom, A.C.M. Swinkels, J. de Ruiter, R.M. Boom, P.F.C. Wilms, M.A.I. Schutyser

Journal of Food Engineering, Volume 341, March 2023, 111340


Mechanism of ice nucleation in liquid water on alkali feldspars.
Alice Keinert, Katharina Deck, Tilia Gaedeke, Thomas Leisner, Alexei A. Kiselev

Faraday Discussions, Volume 235, 2022


Effect of chemically induced fracturing on the ice nucleation activity of alkali feldspar.
Alexei A. Kiselev, Alice Keinert, Tilia Gaedeke, Thomas Leisner, Christoph Sutter, Elena Petrishcheva, Rainer Abart

Atmospheric Chemistry and Physics, 21, 11801-11814, 2021


Thermal Imaging of Freezing Drizzle Droplets: Pressure Release Events as a Source of Secondary Ice Particles .
Judith Kleinheins, Alexei Kiselev, Alice Keinert, Matthias Kind, Thomas Leisner

Journal of the Atmospheric Sciences, Volume 78, Issue 5, 01 May 2021


Through-drop imaging of moving contact lines and contact areas on opaque water-repellent surfaces.
Arthur Vieira, Wenjuan Cui, Ville Jokinen, Robin H. A. Ras, Quan Zhou

Soft Matter, Issue 13, 2023


Fluid flow simulations meet high-speed video: Computer vision comparison of droplet dynamics.
S. Kulju, L. Riegger, P. Koltay, K. Mattila, J. Hyväluoma

Journalof Colloid and Interface Science, Volume 522, 15 July 2018, Pages 48-56


Temperature change rate actuated bubble mixing for homogeneous rehydration of dry pre-stored reagents in centrifugal microfluidics.
S. Hin, N. Paust, M. Keller, M. Rombach, O. Strohmeer, R. Zengerle, K. Mitsakakis

Lab on a Chip, Issue 2, 2018




Improved Pt-utilization efficiency of low Pt-loading PEM fuel cell electrodes using direct membrane deposition.
Matthias Breitwieser, Matthias Klingele, Benjamin Britton, Steven Holdcroft, Roland Zengerle, Simon Thiele

Electrochemistry Communications, Volume 60, November 2015, Pages 168-171


Direct deposition of proton exchange membranes enabling high performance hydrogen fuel cells.
Matthias Klingele, Matthias Breitwieser, Roland Zengerle, Simon Thiele

Journal of Materials, Chemistry A, Issue 21, 2015


Semi-contact-writing of polymer molds for prototyping PDMS chips with low surface roughness, sharp edges and locally varying channel heights.
Ludwig Gutzweiler, Fabian Stumpf, Laurent Tanguy, Guenter Roth, Peter Koltay, Roland Zengerle, Lutz Riegger

Journal of Micromechanics and Microengineering, 18 March 2016, 26 045018


Tailoring proton transfer species on the membrane surface: An approach to enhance proton conductivity for polymer electrolyte membrane fuel cell.
Adisak Pokprasert, Suwabun Chirachanchai

Polymer, Volume 265, 16 January 2023, 125583




Direct deposition of proton exchange membranes enabling high performance hydrogen fuel cells.
Matthias Klingele, Matthias Breitwieser, Roland Zengerle, Simon Thiele

Journal of Materials, Chemistry A, Issue 21, 2015


Improving surface properties by laser-based drying, gelation, and densification of printed sol–gel coatings.
Dominik Hawelka, Jochen Stollenwerk, Norbert Pirch, Konrad Wissenbach, Peter Loosen

Journal of Coatings Technology and Research 11, 3-10, 2014


Open microfluidics


Open microfluidic gel electrophoresis: Rapid and low cost separation and analysis of DNA at the nanoliter scale.
Ludwig Gutzweiler, Tobias Gleichmann, Laurent Tanguy, Peter Koltay, Roland Zengerle, Lutz Riegger

Electrophoresis, Volume 38, Issue 13-14, 20 April 2017, Pages 1764-1770


Paper-based open microfluidic platform for protein electrophoresis and immunoprobing.
Stefan Henning, Zhe Shu, Ludwig Gutzweiler, Peter Koltay, Felix von Stetten, Roland Zengerle, Susanna M. Früh

Electrophoresis, Volume 43, Issue 4, February 2022, Pages 621-631


Image acquisition


Robust temperature change rate actuated valving and switching for highly integrated centrifugal microfluidics.
M. Keller, G. Czilwik, J. Schott, I. Schwarz, K. Dormanns, F. von Stetten, R. Zengerle, N. Paust

Lab on a Chip, Issue 5, 2017


System-level network simulation for robust centrifugal-microfluidic lab-on-a-chip systems.
I. Schwarz, S. Zehnle, T. Hutzenlaub, R. Zengerle, N. Paust

Lab on a Chip, Issue 10, 2016


LabDisk with complete reagent prestorage for sample-to-answer nucleic acid based detection of respiratory pathogens verified with influenza A H3N2 virus.
F. Stumpf, F. Schwemmer, T. Hutzenlaub, D. Baumann, O. Strohmeier, G. Dingemanns, G. Simons, C. Sager, L. Plobner, F. von Stetten, R. Zengerle, D. Mark

Lab on a Chip, Issue 1, 2016




The smaller, the better? The size effect of alginate beads carrying plant growth-promoting bacteria for seed coating.
Teresa Berninger, Birgit Mitter, Claudia Preininger

Journal of Microencapsulation, Micro an Nano Carriers, Volume 33, 2016 - Issue 2