Protein crystallization

Revolutionize your protein crystallography experiments with automation to enhance reproducibility and cost-effectiveness.

Time-consuming and expensive experiments become streamlined, ensuring stable and comparable results through automated processes. Our technology handles low-volumes adeptly, minimizing the consumption of valuable materials. Elevate the efficiency of your experiments, making protein crystallography more accessible and resource-efficient.

 

Save expensive reagent

Enhance your laboratory's resource management with our cutting-edge PIPEJET® technology. Designed for optimal efficiency, PIPEJET® enables the aspiration of minimal sample volumes from source plates with exceptional precision. The dead volume within PIPEJET® pipes is reduced to mere microliters, ensuring highly efficient sample transfer to protein crystallography plates. By minimizing waste and maximizing the utilization of valuable stock materials, our precision-driven solutions empower you to achieve greater experimental efficiency and cost-effectiveness.

Choose PIPEJET® to optimize your research workflows and make the most of your laboratory resources.

Sitting drop

Enhance your protein crystallography experiments with precise droplet dispensing from 2 to 70 nanoliters on crystallography plates.

Cost Efficiency: Reduce reagent costs with small volume transfers.  
Enhanced Productivity: Boost the number of crystallization runs with our optimized system.  
Contamination Prevention: Lower contamination risks with controlled droplet deposition.  
Reproducibility: Ensure reliable, reproducible experimental results.

Choose our technology for a more efficient and cost-effective protein crystallography workflow.

Relevant literature

On-demand droplet loading of ultrasonic acoustic levitator and its application for protein crystallography experiments | 2019

In this Letter, we explore a method of loading small droplets by using DoD dispensers to eject droplets and capturing those by the acoustic levitator. By analyzing the required condition for the trapping, we have developed a stable trapping strategy and applied the method to conduct a pilot protein crystallography experiment. In this way, we showed that the combination of the DoD dispensing method with the ALD is promising to realize an automated X-ray diffraction experiment without solid containers for crystals.

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Automated harvesting and processing of protein crystals through laser photoablation

Currently, macromolecular crystallography projects often require the use of highly automated facilities for crystallization and X-ray data collection. However, crystal harvesting and processing largely depend on manual operations. Here, a series of new methods are presented based on the use of a low X-ray-background film as a crystallization support and a photoablation laser that enable the automation of major operations required for the preparation of crystals for X-ray diffraction experiments.

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